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Process analytical technology (PAT) tools for the cultivation step in biopharmaceutical production

Streefland, Mathieu, Martens, Dirk E., Beuvery, E. Coen, Wijffels, René H.

Journal:

Engineering in Life Sciences

Année:

2013

Langue:

english

Fichier:

PDF, 617 KB

english, 2013

Analytical Approaches to the Study of Monoclonal Antibody Stability

Wim Jiskoot, E. Coen Beuvery, Ada A. M. de Koning, James N. Herron, Daan J. A. Crommelin

Journal:

Pharmaceutical Research

Année:

1990

Fichier:

PDF, 1.74 MB

1990

Simultaneous administration of oral rhesus-human reassortant tetravalent (RRV-TV) rotavirus vaccine and oral poliovirus vaccine (OPV) in Thai infants

Sricharoen Migasena, Sriluck Simasathien, Rudiwilai Samakoses, Punnee Pitisuttitham, Preyapan Sangaroon, Gijsbert van Steenis, E. Coen Beuvery, Helen Bugg, Ruth Bishop, Bruce L. Davidson, Timo Vesikar

Journal:

Vaccine

Année:

1995

Langue:

english

Fichier:

PDF, 1.08 MB

english, 1995

Preparation of clinical grade monoclonal antibodies from serum-containing cell culture supernatants

Wim Jiskoot, Jos J.C.C. Van Hertrooij, Anna-Myra V. Hoven, Jacqueline W.T.M. Klein Gebbinck, Tiny Van der Velden-de Groot, Daan J.A. Crommelin, E. Coen Beuvery

Journal:

Journal of Immunological Methods

Année:

1991

Langue:

english

Fichier:

PDF, 768 KB

english, 1991

Rational medium design for Bordetella pertussis: basic metabolism

Marcel Thalen, Jan van den IJssel, Wim Jiskoot, Bert Zomer, Paul Roholl, Cornelis de Gooijer, Coen Beuvery, Johannes Tramper

Journal:

Journal of Biotechnology

Année:

1999

Langue:

english

Fichier:

PDF, 338 KB

english, 1999

Comparison of Enhanced Potency Inactivated Poliovirus Vaccine (EIPV) Versus Standard Oral Poliovirus Vaccine (OPV) in Thai Infants

Simasathien, Sriluck, Migasena, Sricharoen, Beuvery, Coen, Steenis, Gijsbert Van, Samakoses, Rudiwilai, Pitisuttitham, Punnee, Vesikari, Timo

Journal:

Scandinavian Journal of Infectious Diseases

Année:

1994

Langue:

english

Fichier:

PDF, 513 KB

english, 1994

Manufacturing Vaccines: An Illustration of Using PAT Tools for Controlling the Cultivation of Bordetella pertussis

van Sprang, Eric N. M., Streefland, Mathieu, Ramaker, Henk-Jan, van der Pol, Leo A., Beuvery, E. Coen, Smilde, Age. K.

Journal:

Quality Engineering

Année:

2007

Langue:

english

Fichier:

PDF, 845 KB

english, 2007

Modeling Neisseria meningitidis B metabolism at different specific growth rates

Gino J.E. Baart, Marieke Willemsen, Elnaz Khatami, Alex de Haan, Bert Zomer, E. Coen Beuvery, Johannes Tramper, Dirk E. Martens

Journal:

Biotechnology and Bioengineering

Année:

2008

Langue:

english

Fichier:

PDF, 395 KB

english, 2008

Evaluation of a critical process parameter: Oxygen limitation during cultivation has a fully reversible effect on gene expression of Bordetella pertussis

Mathieu Streefland, Bas van de Waterbeemd, Joeri Kint, Leo A. van der Pol, E. Coen Beuvery, Johannes Tramper, Dirk E. Martens

Journal:

Biotechnology and Bioengineering

Année:

2009

Langue:

english

Fichier:

PDF, 310 KB

english, 2009

Gene-expression-based quality scores indicate optimal harvest point in Bordetella pertussis cultivation for vaccine production

Bas van de Waterbeemd, Mathieu Streefland, Jeroen Pennings, Leo van der Pol, Coen Beuvery, Johannes Tramper, Dirk Martens

Journal:

Biotechnology and Bioengineering

Année:

2009

Langue:

english

Fichier:

PDF, 434 KB

english, 2009

Methods for studying the stability of antibody expression by hybridoma cells in homogeneous continuous culture systems

Jose M Coco-Martin, Jan W Oberink, Tiny A.M van der Velden-de Groot, E.Coen Beuvery

Journal:

Analytica Chimica Acta

Année:

1991

Langue:

english

Fichier:

PDF, 495 KB

english, 1991

Preparation and application of a fluorescein-labeled peptide for determining the affinity constant of a monoclonal antibody-hapten complex by fluorescence polarization

Wim Jiskoot, Peter Hoogerhout, E.Coen Beuvery, James N. Herron, Daan J.A. Crommelin

Journal:

Analytical Biochemistry

Année:

1991

Langue:

english

Fichier:

PDF, 620 KB

english, 1991

Immunisation against bacterial meningitis

E. Coen Beuvery

Journal:

Journal of Infection

Année:

1981

Langue:

english

Fichier:

PDF, 568 KB

english, 1981

Animal cell culture: Towards the 21st century

E. Coen Beuvery

Journal:

Cytotechnology

Année:

1995

Langue:

english

Fichier:

PDF, 158 KB

english, 1995

Preparation of liposomes via detergent removal from mixed micelles by dilution

Wim Jiskoot, Tom Teerlink, E. Coen Beuvery, Daan J. A. Crommelin

Journal:

International Journal of Clinical Pharmacy

Année:

1986

Langue:

english

Fichier:

PDF, 719 KB

english, 1986

The potential of flow cytometric analysis for the characterization of hybridoma cells in suspension cultures

José M. Coco-Martin, Jan W. Oberink, Tiny A. M. van der Velden-de Groot, E. Coen Beuvery

Journal:

Cytotechnology

Année:

1992

Langue:

english

Fichier:

PDF, 873 KB

english, 1992

Viability measurements of hybridoma cells in suspension cultures

José M. Coco-Martin, Jan W. Oberink, Tiny A. M. van der Velden-de Groot, E. Coen Beuvery

Journal:

Cytotechnology

Année:

1992

Langue:

english

Fichier:

PDF, 638 KB

english, 1992

Application of Electrospray Mass Spectrometry (ES-MS) for the Analysis of Monoclonal Antibody FcSubunits

Wim Jiskoot, Gerrit van de Werken, José M. Coco Martin, Brian N. Green, E. Coen Beuvery, Daan J. A. Crommelin

Journal:

Pharmaceutical Research

Année:

1992

Fichier:

PDF, 1.00 MB

1992

The Influence of Sucrose, Dextran, and Hydroxypropyl-β-cyclodextrin as Lyoprotectants for a Freeze-Dried Mouse IgG2aMonoclonal Antibody (MN12)

Maaike E. Ressing, Wim Jiskoot, Herre Talsma, Cor W. van Ingen, E.Coen Beuvery, Daan J. A. Crommelin

Journal:

Pharmaceutical Research

Année:

1992

Fichier:

PDF, 1.39 MB

1992

Quantification of Cell-Associated and Free Antigens in Bordetella pertussis Suspensions by Antigen Binding ELISA

Westdijk, Janny, van den Ijssel, Jan, Thalen, Marcel, Beuvery, Coen, Jiskoot, Wim

Journal:

Journal of Immunoassay

Année:

1997

Langue:

english

Fichier:

PDF, 730 KB

english, 1997

Potency of Wild-type or Sabin Trivalent Inactivated Poliovirus Vaccine, by Enzyme-Linked Immunosorbent Assay using Monoclonal Antibiotics Specific for Each Antigenic Site

Leigh A. Sawyer, David Wood, Morag Ferguson, Radu Crainic, E.Coen Beuvery, Jonathan McInnis, Paul Albrecht

Journal:

Biologicals

Année:

1997

Langue:

english

Fichier:

PDF, 80 KB

english, 1997

Fed-batch cultivation of Bordetella pertussis: Metabolism and Pertussis Toxin production

Marcel Thalen, Marian Venema, Anita Dekker, Luc Berwald, Jan van den IJssel, Bert Zomer, Coen Beuvery, Dirk Martens, Johannes Tramper

Journal:

Biologicals

Année:

2006

Langue:

english

Fichier:

PDF, 375 KB

english, 2006

Effect of relevant culture parameters on Pertussis Toxin expression by Bordetella pertussis

Marcel Thalen, Marian Venema, Jan van den IJssel, Luc Berwald, Coen Beuvery, Dirk Martens, Johannes Tramper

Journal:

Biologicals

Année:

2006

Langue:

english

Fichier:

PDF, 300 KB

english, 2006

Non-random conformation of a mouse IgG2a monoclonal antibody at low pH

Wim JISKOOT, Michael BLOEMENDAL, Bart van HAERINGEN, Rienk van GRONDELLE, E. Coen BEUVERY, James N. HERRON, Daan J. A. CROMMELIN

Journal:

FEBS Journal

Année:

1991

Langue:

english

Fichier:

PDF, 1.14 MB

english, 1991

On the structure of immune-stimulating saponin-lipid complexes (iscoms)

Gideon F.A. Kersten, Arjen Spiekstra, E. Coen Beuvery, Daan J.A. Crommelin

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

1991

Langue:

english

Fichier:

PDF, 2.01 MB

english, 1991

Analysis of glycoforms present in two mouse IgG2a monoclonal antibody preparations

JoséM. Coco-Martin, Freek Brunink, Tiny A.M. van der Velden-de Groot, E. Coen Beuvery

Journal:

Journal of Immunological Methods

Année:

1992

Langue:

english

Fichier:

PDF, 476 KB

english, 1992

PAT for vaccines: The first stage of PAT implementation for development of a well-defined whole-cell vaccine against whooping cough disease

Mathieu Streefland, Bas van de Waterbeemd, Hester Happé, Leo A. van der Pol, E. Coen Beuvery, Johannes Tramper, Dirk E. Martens

Journal:

Vaccine

Année:

2007

Langue:

english

Fichier:

PDF, 414 KB

english, 2007

Scale-up for bulk production of vaccine against meningococcal disease

Gino J.E. Baart, Govert de Jong, Marvin Philippi, Klaas van’t Riet, Leo A. van der Pol, E. Coen Beuvery, Johannes Tramper, Dirk E. Martens

Journal:

Vaccine

Année:

2007

Langue:

english

Fichier:

PDF, 484 KB

english, 2007

Improving the cellular pertussis vaccine: Increased potency and consistency

Marcel Thalen, Arno van der Ark, Jan van den IJssel, Ineke van Straaten, Dennis Jansen, Coen Beuvery, Dirk Martens, Johannes Tramper

Journal:

Vaccine

Année:

2008

Langue:

english

Fichier:

PDF, 578 KB

english, 2008

Chitosan microparticles for mucosal vaccination against diphtheria: oral and nasal efficacy studies in mice

Inez M. van der Lubben, Gideon Kersten, Marjan M. Fretz, Coen Beuvery, J. Coos Verhoef, Hans E. Junginger

Journal:

Vaccine

Année:

2003

Langue:

english

Fichier:

PDF, 163 KB

english, 2003

Immunogenicity of a pilot inactivated poliovirus vaccine with trypsin-treated type 3-component

Liisa Piirainen, Merja Roivainen, Leila Litmanen, Juhani Eskola, E.Coen Beuvery, Tapani Hovi

Journal:

Vaccine

Année:

1997

Langue:

english

Fichier:

PDF, 724 KB

english, 1997

Single shot with tetanus toxoid in biodegradable microspheres protects mice despite acid-induced denaturation of the antigen

Gideon F.A. Kersten, Dian Donders, Arnoud Akkermans, E.Coen Beuvery

Journal:

Vaccine

Année:

1996

Langue:

english

Fichier:

PDF, 728 KB

english, 1996

Randomised, controlled trial with the trypsin-modified inactivated poliovirus vaccine: assessment of intestinal immunity with live challenge virus

Liisa Piirainen, Mirja Stenvik, Merja Roivainen, Juhani Eskola, E.Coen Beuvery, Tapani Hovi

Journal:

Vaccine

Année:

1999

Langue:

english

Fichier:

PDF, 141 KB

english, 1999

Antigenic and immunogenic properties of inactivated polio vaccine made from Sabin strains

Gideon Kersten, Ton Hazendonk, Coen Beuvery

Journal:

Vaccine

Année:

1999

Langue:

english

Fichier:

PDF, 910 KB

english, 1999

Characterization of Diphtheria Toxoid

GIDEON KERSTEN, WIM JISKOOT, TON HAZENDONK, ARJEN SPIEKSTRA, JANNY WESTDIJK, COEN BEUVERY

Journal:

Journal of Pharmacy and Pharmacology

Année:

1999

Langue:

english

Fichier:

PDF, 77 KB

english, 1999

Two-step purification of a murine monoclonal antibody intended for therapeutic application in man: Optimisation of purification conditions and scaling up

Wim Jiskoot, Jos J.C.C. Van Hertrooij, Jacqueline W.T.M. Klein Gebbinck, Tiny Van der Velden-de Groot, Daan J.A. Crommelin, E.Coen Beuvery

Journal:

Journal of Immunological Methods

Année:

1989

Langue:

english

Fichier:

PDF, 1.28 MB

english, 1989

Purification and stabilization of a poorly soluble mouse IgG3 monoclonal antibody

Wim Jiskoot, Anna-Myra V. Hoven, Ada A.M. De Koning, Mia F. Leerling, C.H.Karin Reubsaet, Daan J.A. Crommelin, E.Coen Beuvery

Journal:

Journal of Immunological Methods

Année:

1991

Langue:

english

Fichier:

PDF, 555 KB

english, 1991

Preparation and characterization of liposomes with incorporated Neisseria gonorrhoeae protein ib and amphiphilic adjuvants

Frans van Dalen, Gideon Kersten, Tom Teerlink, E.Coen Beuvery, Daan J.A. Crommelin

Journal:

Journal of Controlled Release

Année:

1988

Langue:

english

Fichier:

PDF, 1022 KB

english, 1988

O-Polysaccharide-protein conjugates induce high levels of specific antibodies to Pseudomonas aeruginosa immunotype 3 lipopolysaccharide

Paul A. van de Wiel, Maarten H. Witvliet, Dolf Evenberg, Henk J.G.M. Derks, E. Coen Beuvery

Journal:

Vaccine

Année:

1987

Langue:

english

Fichier:

PDF, 607 KB

english, 1987

Synergistic effect of detergents and aluminium phosphate on the humoral immune response to bacterial and viral membrane proteins

Tom Teerlink, E. Coen Beuvery, Dolf Evenberg, Toon L. van Wezel

Journal:

Vaccine

Année:

1987

Langue:

english

Fichier:

PDF, 988 KB

english, 1987

Characterization of Antibody Labelled Colloidal Gold Particles and Their Applicability in a Sol Particle Immuno Assay (SPIA)

Cocco Martin, José M., P[acaron]ques, Marcel, van der Velden-de Groot, Tiny A. M., Beuvery, E. Coen

Journal:

Journal of Immunoassay

Année:

1990

Langue:

english

Fichier:

PDF, 584 KB

english, 1990

Instability of a Hybridoma Cell Line in a Homogeneous Continuous Perfusion Culture System

COCO-MARTIN, JOSÉ M., OBERINK, JAN W., BRUNINK, FREEK, VAN DER VELDEN-DE GROOT, TINY A. M., BEUVERY, E. COEN

Journal:

Hybridoma

Année:

1992

Langue:

english

Fichier:

PDF, 1007 KB

english, 1992

Inactivated Poliovirus Vaccine Protects Transgenic Poliovirus Receptor Mice against Type 3 Poliovirus Challenge

Rolf E. Taffs, Yelena V. Chernokhvostova, Eugenia M. Dragunsky, Tatsuji Nomura, Kyoji Hioki, E. Coen Beuvery, Edward A. Fitzgerald, Inessa S. Levenbook and David M. Asher

Journal:

The Journal of Infectious Diseases

Année:

1997

Langue:

english

Fichier:

PDF, 881 KB

english, 1997

Supplement 1. Epidemiology, Pathogenesis, and Prevention of Haemophilus influenzae Disease || Preparation, Antigenicity, and Immunogenicity of Synthetic Ribosylribitol Phosphate Oligomer-Protein Conjugates and Their Potential Use for Vaccination against Haemophilus influenzae Type b Disease

Dolf Evenberg, Peter Hoogerhout, Constant A. A. van Boeckel, Ger T. Rijkers, E. Coen Beuvery, Jacques H. van Boom and Jan T. Poolman

Journal:

The Journal of Infectious Diseases

Année:

1992

Langue:

english

Fichier:

PDF, 723 KB

english, 1992

On-Line Harvest Prediction for the Production of Biologicals

Neeleman, Ronald, Joerink, Michiel, van Boxtel, Ton, Beuvery, Coen, van Straten, Gerrit

Journal:

IFAC Proceedings Volumes

Année:

2001

Langue:

english

Fichier:

PDF, 507 KB

english, 2001